Peritoneal Mesothelioma - Summary, Diagnosis & Treatment

[Summary]

Peritoneal malignant mesothelioma, also known as primary peritoneal mesothelioma, and originated in peritoneal mesothelial organizations epithelial tumors. This rare disease than pleural mesothelioma, slightly higher than the male female. Etiology and asbestos exposure, the incidence and contacts for a long interval, and often in more than 30 years. Mesothelioma often benign single, located in the fallopian tubes, uterus top of the peritoneum, rare in other parts. Often diffuse malignant mesothelioma, covering all or part of peritoneal


[Diagnosis]

1. History questions

The exact cause of the abdominal pain, abdominal distension and gastrointestinal disorders, abdominal pain may be in for diversification, but the pain of the stubbornness of its common characteristics. The high incidence of ascites, in more than 90 per cent, in a longer or shorter period of abdominal pain, ascites suddenly appeared, but also in the early ascites appeared individually. The amount of ascites and stubborn. General situation in the longer term, little change, loss of appetite can be maintained, wasting not obvious, no fever, sometimes spontaneous hypoglycemia can occur. Can be associated with chest pain, difficulty breathing, coughing and other symptoms of pleural mesothelioma.

2. Medical examination found

Peng Long abdomen, or a frog belly, mobility voiced positive abdominal palpation can be touched on the size ranging from single or multiple masses, the general tenderness not obvious. As with pleural mesothelioma, pleural effusion can be found positive signs.

3. Laboratory examination

B-ultrasound and CT, can be found thin sheet of images and ascites tumor. Ascites for exudate, but also for the courage and uprightness. Hyaluronic acid such as ascites increased to 120 ug / ml, very helpful in the diagnosis. Ascites find new biological diagnosis of mesothelioma cells, but also the middle of the mesothelial cells of ascites chromosome analysis, help diagnosis. Laparoscopic seized visible peritoneal surface filled with plaques and nodules, and biopsy examination to confirm the diagnosis. It must be noted and tuberculous peritonitis, peritoneal metastasis of identification.



[Treatment]

General chemotherapy and radiotherapy are not satisfied with the results. Some reports in recent years with adriamycin treatment, 50% of cases of extended survival period, but there are also reports considered invalid. It was also advocate the use of immune therapy, needed further observation. General in the diagnosis of 1 ~ 2 years after death.